We are pleased to announce the publication of our most recent paper titled "Prevention Is the Best Treatment: The Case for Understanding the Transition from Monoclonal Gammopathy of Undetermined Significance to Myeloma," which is free to view here. Screening and prevention strategies have been used successfully in some solid tumor cancers, including breast, colon, and prostate. … Continue reading Lab Publishes New Paper on Preventing Multiple Myeloma
Last week our lab came together in the Clinical Research Unit at the University of Iowa to film the online supplement to our paper titled "Combining volumetric capnography and barometric plethysmography to measure the lung structure-function relationship." This method allows the investigator to measure the volume of the airways at different lung volumes, to more … Continue reading Lab films methods video on measuring the lung structure-function relationship!
A focus of our laboratory is understanding the regulation of pulmonary blood vessels by hypoxia, including non-canonical intrapulmonary shunt vessels. While we still don’t understand a lot about their structure, we recently found that they are regulated (in part) by the beta-2 adrenergic pathway. Beta-2 adrenergic receptors cause dilation (or widening) of blood vessels in the … Continue reading New paper accepted in Frontiers in Physiology!
Work completed with our collaborators in Naomi Chesler’s laboratory has been accepted for publication in the Journal of Biomechanics! The paper titled “Pulmonary arterial strain- and remodeling-induced stiffening are differentiated in a chronic model of pulmonary hypertension ” reports our finding that chronic thromboembolic pulmonary hypertension causes stiffening of the large elastic arteries and that this is … Continue reading New Paper Accepted in the Journal of Biomechanics!!
SourceMultiple myeloma is an incurable plasma cancer and the second most common blood malignancy. We have been interested in the role oxygen plays in mediating the progression of this disease and our new collaboration with the Translational Myeloma Group at the University of Iowa has yielded it’s first publication in the journal Oncotarget. We are glad … Continue reading New Paper Accepted in Oncotarget!